Professor Yehuda Shoenfeld, WAidid board member, suggests the editorial of the last issue of Lupus: "Haemophagocytic lymphohistiocytosis: from diagnostic challenges to predictive possibilities"

AUTHORS: A. Soriano & Y. Shoenfeld

SUMMARY
Given the increasing insights into the pathogenesis of several autoimmune and autoinflammatory disorders, and thanks to the rapid and continuous improvement of the diagnostic techniques, we are currently living in the era of the prediction of autoimmune diseases. Whereas the autoimmune (or autoinflammatory) disease has already been manifested, the current and future challenge is to detect predictive markers of the response to treatment and of relapse, the latter becoming more and more sophisticated and personalized, according to the new pathogenic acquisitions.

In this editorial the authors had briefly revisited the history of HLH since the first pathological observations in order to underline as the progression of the pathogenic insights proceeds accordingly to the scientific technical advances, especially in the case of rare conditions. HLH is a valid example of the plenty of still-open challenges we are facing in the field of autoimmune and autoinflammatory diseases.

Click here to download the article: Soriano & Shoenfeld - Haemophagocytic lymphohistiocytosis