Nowadays, elderly travel more frequently and longer distance than in the past and in these cases they are often exposed to lot of bacteria they are not used to in their home countries. Before leaving on a trip, prof. Chidiac (Lyon, France) suggests, they should check that the routine immunization is ok (tetanus, poliomyelitis, difteria, and sometimes pertussis) and then discuss with the physician the best immunization strategy: some vaccines are well tolerated and easy to administered (typhoid fever, A hepatitis) but in some other cases the older the patient, the less the immune response or the riskier the side effects and therefore it is necessary to evaluate the benefit balance.