This week, WAidid suggests the article Risk Factors for Community-associated Clostridium difficile–associated Diarrhea in children.

SUMMARY: 

Clostridium difficile -associated diarrhea (CDAD) is increasingly diagnosed in children in community settings. This study aims to assess  recent antibiotic use and other risk factors in children with community- associated (CA-) CDAD compared with children with other diarrheal illnesses in a tertiary care setting.
The authours ecompared 69 children with CA-CDAD to 138 children with non- C. difficile, community-associated diarrhea, and found  that cephalosporin use within 30 days and the use of gastrointestinal feeding devices were independently associated with pediatric CA-CDAD. This study is the first to identify risk factors for CA- CDAD in a pediatric population. Recent use of cephalosporins and the presence of gastrointestinal feeding devices are important risk factors for community-associated CDAD in children. Reduction in the use of outpatient antibiotics may decrease the burden of CA-CDAD in children.

AUTHORS: Crews JD, Anderson LR, Waller DK, Swartz MD, DuPont HL, Starke JR.

To read the abstract online, click here.